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This instructional program class comprises any program that focuses on the scientific study of the expression, initiation, maintenance and progression of tissue injury and disease, including death, and the relationship of pathogenesis to fundamental molecular and cellular mechanisms. These programs include courses in immunology, microbiology, gene expression, inflammation, cell injury, apoptosis, immunopathology, molecular markers of disease and toxins, neoplasia, growth regulation, and organ- and system-specific investigations.